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目的:针对2型糖尿病患者实施甘精胰岛素联合瑞格列奈治疗,观察及分析疗效情况。方法:选取2型糖尿病患者120例,随机分成研究组、参照组,两组病例数一致。将皮下注射预混胰岛素治疗方案应用于参照组患者,给予研究组患者甘精胰岛素联合瑞格列奈的方式治疗,观察及对比治疗的效果。结果:通过采取相异形式的治疗方案,研究组患者获得的总体治疗有效率同参照组相对比优势明显,并且不良反应情况也显著的少于参照组,P值均<0.05;此外,对比两组患者治疗以后的空腹血糖、餐后2 h血糖以及糖化血红蛋白情况,研究组的效果更为理想,同参照组相对比差异性明显,P<0.05。结论:对2型糖尿病患者实施积极有效的治疗方案尤为重要,采取甘精胰岛素联合瑞格列奈的治疗方式可以获得较高的治疗效果。
Objective: To carry out insulin glargine and repaglinide for patients with type 2 diabetes mellitus, observe and analyze the curative effect. Methods: A total of 120 patients with type 2 diabetes mellitus were randomly divided into study group and reference group, with the same number of cases. Subcutaneous injection of premixed insulin treatment regimen was applied to the reference group of patients, the study group patients with glargine combined with repaglinide treatment, observation and comparison of the effect of treatment. Results: By taking different forms of treatment, the total effective rate of treatment in the study group was significantly higher than that in the reference group, and the adverse reactions were also significantly less than those in the reference group (P <0.05). In addition, The fasting blood glucose, 2-hour postprandial blood glucose and glycosylated hemoglobin were better in the study group than in the control group (P <0.05). Conclusion: It is particularly important to implement active and effective treatment for type 2 diabetes patients. The treatment with glargine and repaglinide can achieve a higher therapeutic effect.