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目的:观察集束化护理对CIK细胞治疗肝癌患者生活质量及焦虑的影响。方法:将60例患者随机分为对照组和观察组各30例,对照组患者实施常规护理,观察组患者在常规护理基础上实施集束化护理策略,护理前后采用生活质量量表EORTC QLQ-C30和焦虑量表(SAS量表)通过自身前后交叉对照及组间对照,对患者生活质量和焦虑进行评价。结果:观察组生活质量中躯体功能、角色功能、情绪功能、认识功能、社会功能、疲倦、食欲、腹泻和总体健康优于护理前,差异均有统计学意义(P<0.05);观察组生活质量中的角色功能、情绪功能、认识功能、社会功能、恶心呕吐、呼吸、食欲、便秘、腹泻、经济困难和总体健康较对照组有改善,差异均有统计学意义(P<0.05)。护理后观察组焦虑降低优于对照组,差异有统计学意义(P<0.01)。结论:集束化护理应用于CIK细胞治疗肝癌能更好地改善患者的生活质量和降低患者的焦虑情况。
Objective: To observe the effect of cluster nursing on quality of life and anxiety of patients with hepatocellular carcinoma treated by CIK cells. Methods: Sixty patients were randomly divided into control group and observation group, 30 cases in each group. Patients in control group were given routine nursing care. Patients in observation group were treated with standardized nursing care based on routine nursing care. Quality of life questionnaire EORTC QLQ-C30 And anxiety scale (SAS scale) were used to evaluate the quality of life and anxiety of the patients through their own cross-control and inter-group control. Results: The quality of life in the observation group was significantly better than that before nursing (P <0.05), body function, role function, emotional function, cognitive function, social function, tiredness, appetite, diarrhea and overall health were better than those in the observation group The quality of the function, emotional function, cognitive function, social function, nausea and vomiting, respiratory, appetite, constipation, diarrhea, economic difficulties and overall health than the control group improved, the difference was statistically significant (P <0.05). After treatment, the anxiety reduction in the observation group was better than that in the control group, with significant difference (P <0.01). Conclusions: Cluster therapy can be used to improve the quality of life and reduce anxiety in patients with hepatocellular carcinoma treated with CIK cells.