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目的:探讨醒脑静注射液对感染性发热的干预作用。方法:将210例急性感染性发热患者按感染的判定标准分为病毒组115例与细菌组95例,病毒组随机分为治疗A组65例和对照A组50例;细菌组分为治疗B组52例和对照B组43例。对照组常规治疗,治疗组加用醒脑静治疗。比较各组体温变化、醒脑静注射液对发热的干预。结果:治疗A组用药后2 h、4 h的退热效果、退热时间(4.3±2.7)h、发热次数(3.0±1.4)次、疗程(3.8±1.6)d均显著优于对照A组(P<0.01);治疗B组4h的退热效果和退热时间(6.5±3.3)h明显优于对照B组(P<0.05);但发热次数(5.5±1.8)次和疗程(7.3±2.4)d无明显改善(P>0.05)。结论:醒脑静注射液对病毒感染性发热退热有效、迅速,减少再发热,有效缩短病程,能明显干预病毒感染所致的发热过程。
Objective: To investigate the effect of Xingnaojing injection on infectious fever. Methods: According to the criteria of infection, 210 cases of acute infectious fever were divided into 115 cases of virus group and 95 cases of bacterial group. The virus group was randomly divided into treatment group A (n = 65) and control group A (n = 50) Group 52 cases and control group B 43 cases. Control group conventional treatment, treatment group plus Xingnaojing treatment. Compare the changes of body temperature, Xingnaojing injection on fever intervention. Results: The antipyretic effect, the fever time (4.3 ± 2.7) h, the number of fever (3.0 ± 1.4) and the course of treatment (3.8 ± 1.6) d after treatment for 2 and 4 hours in group A were significantly better than those in control group A (P <0.01). The antipyretic effect and antipyretic time of group B at 4h were significantly better than that of control group B (P <0.05), but the number of fever (5.5 ± 1.8) and the duration of treatment 2.4) d no significant improvement (P> 0.05). Conclusion: Xingnaojing injection can effectively and rapidly relieve the fever caused by virus infection and reduce reheating, effectively shorten the course of the disease, and can significantly interfere with the fever process caused by virus infection.