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目的:观察血小板平均容积(MPV)与急性心肌梗死(AMI)患者溶栓治疗后梗死相关动脉(IRA)再通的关系,确定AMI患者溶栓治疗后冠状动脉再通的一个简明的预测指标。方法:对158例AMI静脉溶栓患者测定MPV,MPV≥9.0 fl为观察组,MPV<9.0 fl为对照组,比较两组IRA再通情况。结果:观察组IRA再通率为73.7%,低于对照组的89.8%(P<0.05)。结论:MPV增大的AMI溶栓治疗再通率低,需及时调整治疗方案,及时准备直接经皮冠状动脉介入治疗(PCI)开通IRA。
OBJECTIVE: To observe the relationship between platelet mean volume (MPV) and recanalization of infarct-related artery (IRA) after thrombolysis in patients with acute myocardial infarction (AMI) and to determine a concise predictor of recanalization of coronary artery after AMI. Methods: MPV was measured in 158 patients with AMI intravenous thrombolysis, MPV≥9.0 fl was observed in the observation group, MPV <9.0 fl was used as the control group, and the recanalization of IRA was compared between the two groups. Results: The IRA recanalization rate in observation group was 73.7%, which was lower than 89.8% in control group (P <0.05). CONCLUSIONS: Increased recanalization rate of AMI with thrombolysis in AMI is low, and the treatment regimen needs to be adjusted in time to prepare for immediate percutaneous coronary intervention (PCI) to open the IRA.