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目的研究医院临床分离嗜麦芽窄食单胞菌的耐药性,指导合理使用抗菌药物。方法采用临床标本分离鉴定和药敏试验方法,对某医院老年病房住院患者感染标本进行病原菌分离鉴定和耐药性观察。结果该医院老年病区在2011-2012年从感染患者病原学标本中共检出嗜麦芽窄食单胞菌72例。临床分离菌株对复方新诺明和米诺环素敏感率在90%以上;但对亚胺培南耐药率达到100%;对其他抗菌药物也不同程度耐药。结论临床分离的嗜麦芽窄食单胞菌只对少数抗菌药物敏感,对多数抗菌药物不同程度耐药,应加强药敏试验,合理使用抗菌药物。
Objective To study the clinical isolates of Stenotrophomonas maltophilia drug resistance, to guide the rational use of antimicrobial agents. Methods Separation and identification of clinical specimens and drug susceptibility testing methods were used to isolate and identify pathogenic bacteria in inpatients infected with geriatric ward in a hospital and the drug resistance was observed. Results 72 cases of Stenotrophomonas maltophilia were detected from the etiological specimens of infected patients in the geriatric ward of the hospital from 2011 to 2012. The sensitivity of the clinically isolated strains to cotrimoxazole and minocycline was over 90%; but the resistance rate to imipenem reached 100%; resistance to other antibiotics was also observed. Conclusions The clinically isolated Stenotrophomonas maltophilia is sensitive to only a few antimicrobial agents and resistant to most antimicrobial agents. It is necessary to strengthen the antimicrobial susceptibility test and rational use of antimicrobial agents.