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本文通过40例胸腺瘤的病理组织学分析,按瘤组织中淋巴细胞数量的多少分为四级。O级淋巴细胞<1/10,I级为2/10～3/10,Ⅱ级为4/lO～6/10,Ⅲ级者为7/10～9/10。通过分析,发现随着分级的增高,临床症状出现较早,肿瘤包膜多较完整,瘤组织坏死较少见和较少浸润周固组织。因此认为以免疲学角度进行分级,更可说明本瘤生物学特性的差异。另外,本文认为在判断恶性特征上,瘤细胞异形性的意义较大,而核分裂相的多少似无明显联系。本文尚对胸腺瘤的诊断和鉴别诊断进行讨论。
In this paper, 40 cases of thymoma histopathological analysis, according to the number of lymphocytes in the tumor tissue is divided into four levels. O grade lymphocytes <1/10, I grade 2/10 ~ 3/10, Ⅱ grade 4 / lO ~ 6/10, Ⅲ grade for the 7/10 ~ 9/10. Through analysis, we found that as the grade increased, clinical symptoms appeared earlier, the tumor capsule was more complete, tumor necrosis less common and less infiltration of the solid tissue. Therefore, to avoid fatigue from the perspective of grading, but also shows the biological characteristics of the tumor differences. In addition, this article believes that in the determination of malignant features, the significance of tumor atypia, while the number of mitotic phase was not significantly related. This article still on the thymoma diagnosis and differential diagnosis are discussed.