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作者用前瞻性临床研究中心的资料对8例混合型结缔组织疾病(MCTD)的女患者进行了深入地研究,以便了解该综合征的肺部损害程度。依 ILO/uC 分级系统(最初用于尘肺)将胸部 X 线检查结果进行分类。所有病例均进行了镓肺扫描、肺功能测定〔包括呼吸量测定法,肺容量、单次呼吸弥散力(DLCD)及运动试验〕和右心导管插管等检查。在静息情况下所有病均有呼吸困难,其中3例并有慢性咳嗽。2例吸烟
The authors used prospective clinical trial data from 8 women with mixed connective tissue disease (MCTD) to conduct an in-depth study to understand the extent of lung damage in this syndrome. Chest X-ray findings were classified according to the ILO / uC grading system (originally used for pneumoconiosis). All patients underwent gallium-lung scintigraphy, pulmonary function tests (including spirometry, lung volume, single respiratory diffusivity (DLCD) and exercise tests) and right heart catheterization. All patients had dyspnea at rest, 3 of whom had chronic cough. 2 cases of smoking