论文部分内容阅读
作者报告了26例多毛细胞性白血病(以下简称毛白)。全部男性,年龄30~71岁。初诊时,仅4例呈现明显的白血性血象,外周血有容易辨认的多毛细胞。其余22例全血细胞均有不同程度减少,淋巴细胞相对增多,占70~90%;外周血多毛细胞识别困难。骨髓穿刺,26例中20例穿刺失败,成功或具有诊断价值者仅6例。6例中5例由骨髓涂片明确为毛白诊断,其中包括明显白血性的4例。而骨髓于抽的20例,18例由骨髓活检确诊为毛白。病理变化:毛白可部份或全部累及骨髓。部份累及16例,除1例粒细胞和巨核细胞明显增生外,其余骨髓细胞增生正常或轻度增生,切片为斑片状和
The authors report 26 cases of hairy cell leukemia (hereinafter referred to as white). All men, aged 30 to 71 years old. At first visit, only 4 cases showed obvious white blood cells, peripheral blood easily identifiable hair cells. The remaining 22 cases of whole blood cells were reduced to varying degrees, the relative increase in lymphocytes, accounting for 70 to 90%; peripheral blood hair cells difficult to identify. Bone marrow aspirates, 20 cases of puncture failed in 26 cases, only 6 cases were successful or have diagnostic value. Of the 6 cases, 5 were clearly diagnosed with white hair by a smear of bone marrow, including 4 with marked white blood. The bone marrow pumping in 20 cases, 18 cases of bone marrow biopsy diagnosed as white. Pathological changes: Whitening may be involved in part or all of the bone marrow. Partial involvement of 16 cases, in addition to a significant proliferation of granulocytes and megakaryocytes, the remaining bone marrow hyperplasia of normal or mild hyperplasia, the patch is patchy and