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目的探讨超级伽玛刀对肝转移瘤的治疗效果。方法回顾分析我院2006年1月—2010年3月收治的59例肝转移瘤患者(103个转移灶),肿瘤的临床靶体积(CTV)为1.2～247 cm3(平均55.9 cm3),计划靶体积(PTV)周边剂量为每次照射3～6 Gy(平均4.8 Gy),PTV中心剂量为每次照射6～10 Gy(平均8.2 Gy),每天1次,每周5次,共5～12次。结果总有效率(完全缓解+部分缓解)为88.1%。6个月、1年、2年生存率分别为93.0%、72.2%3、1.6%。结论伽玛刀治疗是治疗肝转移瘤的有效方法。
Objective To investigate the therapeutic effect of super gamma knife on liver metastases. Methods The clinical data of 59 patients with metastatic liver metastases (103 metastases) from January 2006 to March 2010 in our hospital were retrospectively analyzed. The clinical target volume (CTV) was 1.2 ~ 247 cm3 (average 55.9 cm3) Peripheral doses of PTV ranged from 3 Gy to 6 Gy per irradiation (mean 4.8 Gy). PTV center doses ranged from 6 Gy to 10 Gy per irradiation (mean 8.2 Gy), once daily and 5 to 12 weeks Times. The total effective rate (complete remission + partial remission) was 88.1%. The 6-month, 1-year and 2-year survival rates were 93.0%, 72.2% 3 and 1.6% respectively. Conclusion Gamma knife treatment is an effective method for the treatment of liver metastases.