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目的观察灯盏花素联合α-硫辛酸治疗糖尿病周围神经病变的疗效。方法 90例糖尿病周围神经病变患者分为2组。治疗组45例,每日给予灯盏花素40 mg,α-硫辛酸600mg。对照组45例,每日给予甲钴胺500μg。2组疗程皆为4周。结果治疗组临床疗效、神经传导速度改善明显优于对照组,差异有统计学意义(P<0.05)。结论灯盏花素联合α-硫辛酸治疗可明显改善糖尿病周围神经病变。
Objective To observe the efficacy of breviscapine combined with α-lipoic acid in the treatment of diabetic peripheral neuropathy. Methods Ninety patients with diabetic peripheral neuropathy were divided into two groups. Treatment group, 45 cases of daily administration of breviscapine 40 mg, α-lipoic acid 600mg. Control group, 45 patients were given methylcobalamin 500μg daily. 2 groups of treatment are 4 weeks. Results The clinical curative effect and nerve conduction velocity of the treatment group were significantly better than those of the control group (P <0.05). Conclusion Breviscapine combined with α-lipoic acid treatment can significantly improve diabetic peripheral neuropathy.