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将2009年11月至2011年11月期间在我院门诊就诊及住院的DM并伴有不同程度的DPN患者92例随机分为A组和B组各46例,在常规治疗的基础上A组给予弥可保治疗,B组给予依帕司他治疗,比较分析两组的治疗效果。结果:A组总有效率95.65%,B组总有效率83.61%,A组明显高于B组,两组比较差异具有统计学意义(P<0.05)。两组治疗前后血尿常规、肝肾功能均无明显变化,也未发现其他药物不良反应。结论:弥可保治疗糖尿病周围神经病疗效高于依帕司他,但两种药物均具有明显的治疗效果。
Ninety-two patients with DPN who were hospitalized and hospitalized in our hospital from November 2009 to November 2011 were randomly divided into A group and B group, with 46 cases in each group. On the basis of routine treatment, group A Give mecoprop treatment, B group given epalrestat treatment, comparative analysis of the two groups of treatment. Results: The total effective rate in group A was 95.65%, the total effective rate in group B was 83.61%. The rate of total effective rate in group A was significantly higher than that in group B, the difference was statistically significant (P <0.05). Before and after treatment, the two groups had no obvious changes in hematuria, liver and kidney function, and no adverse reactions of other drugs were found. Conclusions: The effect of treatment of diabetic peripheral neuropathy is better than that of epalrestat, but both drugs have obvious curative effect.