论文部分内容阅读
方法：实验选用15只新西兰兔，分为3组，每组5只，分别为颈椎间盘退变组、颈椎间盘退变加人工麝香饲养组和正常对照组。通过切除动物颈棘上及棘间韧带和分离颈椎旁两侧肌肉，造成颈椎力学上的失衡而诱导了兔的颈椎间盘退行性变化。在术后8月时，杀死动物．取动物颈椎间盘组织，用单向环状免疫扩散技术测定其中IgG及IgM含量。结果：退变颈椎间盘中IgG含量明显升高；人工麝香具有显著降低退变颈椎间盘中IgG的作用，IgM与颈椎间盘退变无关。
METHODS: Fifteen New Zealand rabbits were selected and divided into 3 groups, 5 in each group. They were cervical disc degeneration group, cervical intervertebral disc degeneration plus artificial musk feeding group and normal control group. By resection of the animal’s cervical spine and the interspinous ligament and the separation of the muscles on both sides of the cervical spine, mechanical imbalances in the cervical spine caused a degenerative change in the cervical disc in rabbits. At 8 months after the operation, animals were killed. Animals were harvested from cervical intervertebral discs and IgG and IgM levels were determined using a unidirectional circular immunodiffusion technique. Results: The content of IgG in degenerative cervical intervertebral discs increased significantly; artificial musk had a significant effect on reducing IgG in degenerative cervical intervertebral discs. IgM was not associated with cervical intervertebral disc degeneration.