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目的:研究溶栓和直接经皮冠状动脉腔内成形术(PTCA)治疗青年人急性心肌梗死(AMI)的疗效。方法:50例40岁以下AMI分成溶栓治疗组(30例)和直接PTCA组(20例),比较梗死相关血管开通率和出院时左心室功能。结果:尿激酶溶栓治疗组血流TIMI级者46.2%(14/30),且存在80%～95%的残余狭窄,出院时左心室射血分数(LVEF)平均45%;直接PTCA治疗组术后血流全部达TIMI 3级(100%),LVEF 60%,明显高于溶栓治疗组。结论:青年人患AMI时,直接PTCA疗效明显高于溶栓治疗,值得推广。
Objective: To study the efficacy of thrombolysis and direct percutaneous transluminal coronary angioplasty (PTCA) in the treatment of young patients with acute myocardial infarction (AMI). Methods: Fifty AMI patients under 40 years old were divided into thrombolysis group (30 cases) and direct PTCA group (20 cases). Infarction-related vascular open rate and left ventricular function were compared. Results: The urokinase thrombolytic therapy group had a TIMI grade of 46.2% (14/30) and a residual stenosis of 80% -95%. The left ventricular ejection fraction (LVEF) at discharge was 45% on average. In the direct PTCA group All patients achieved TIMI grade 3 (100%) and LVEF 60% after operation, which was significantly higher than that of thrombolysis group. Conclusion: When young people suffer from AMI, the direct PTCA efficacy is significantly higher than thrombolytic therapy, which is worth promoting.