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目的:研究孟鲁司特联合吸入用布地奈德混悬液对小儿咳嗽变异性哮喘的治疗效果。方法:按照随机数字表法将2014.11-2015.11入诊我院的86例小儿咳嗽变异性哮喘的患儿分为A、B两组各43例,其中A组使用吸入用布地奈德混悬液雾化进行治疗,B组在A组基础上加用孟鲁司特进行治疗。对比两组患者肺通气功能情况。结果:对比治疗前,两组患儿在VC、FVC以及FEVI方面无较大差异,P>0.05;经过两个月对比治疗,B组患者以上三组数据分别为(0.69±0.13)L、(0.71±0.14)L、(0.69±0.14)L,均优于A组,差异明显。结论:在使用吸入用布地奈德混悬液雾化对小儿咳嗽变异性哮喘患儿进行治疗的基础上联合使用孟鲁司特,对患儿肺部通气功能具有较好的改善作用。
Objective: To study the therapeutic effect of budesonide suspension combined with montelukast on children with cough variant asthma. Methods: A total of 86 children with cough variant asthma admitted to our hospital from November 2014 to November 2015 were randomly divided into two groups (A and B), 43 cases in each group. The patients in group A received inhaled budesonide For treatment, group B was treated with montelukast on the basis of group A. Compare the two groups of patients with pulmonary ventilation function. Results: Before treatment, there was no significant difference in VC, FVC and FEVI between the two groups (P> 0.05). After two months of treatment, the data of the above three groups were (0.69 ± 0.13) L and 0.71 ± 0.14) L and (0.69 ± 0.14) L, respectively, which were all better than that of group A, the difference was obvious. CONCLUSIONS: Montelukast combined with inhalation of budesonide suspension for treatment of pediatric cough variant asthma may improve pulmonary ventilation in children.