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作者在本文中比较了棉酚的左旋异构体、消旋棉酚和醋酸棉酚对雄性金黄田鼠的抗生育作用。研究采用20头雄性、年轻的成年金黄田鼠,体重约100g,置于空调、光照12小时/天的环境中,随机分为4组,每组5头。每鼠每天灌服下述药物一次,连续40天;Ⅰ组-混悬甾体用的赋形剂(SSV);Ⅱ组-醋酸棉酚16mg/kg/d;Ⅲ组-左旋棉酚8mg/kg/d;Ⅳ组-消旋棉酚16mg/kg/d。所有药物溶于SSV中,每周配制一次,药物体积为0.2ml/kg,
In this paper, the authors compared the antifertility effects of L-isomers of gossypol, racemic gossypol and gossypol acetate on male golden voles. Twenty male and young adult golden voles, weighing about 100 g, were housed in an air-conditioned, light-exposed environment for 12 hours / day and were randomly divided into 4 groups of 5 heads each. The rats were drenched with the following drugs once daily for 40 consecutive days: Group I - vehicle for the suspension of steroid (SSV); Group II - Gossypol acetate 16 mg / kg / d; Group III - L-gossypol 8 mg / kg / d; Group Ⅳ - racemic gossypol 16mg / kg / d. All drugs dissolved in SSV, formulated once a week, the drug volume of 0.2ml / kg,