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胎膜早破（PROM）为产科临床最突出问题之一，约占出生总数的4％～7％［1］，亦有报告达10％［2］，常使妊娠提前结束，增加了围生期病率及围生儿死亡率。自80年代以来国内外学者对其进行了大量研究，现综述如下。1定义一般认为胎膜在真正临产前破裂，即为PROM。KUrhi等［3］则
Premature rupture of membranes (PROM) is one of the most prominent obstetric clinical problems, accounting for about 4% to 7% of the total number of births [1], and also reported up to 10% [2], often leads to an early termination of pregnancy, an increase of perinatal Period prevalence and perinatal mortality. Since the 1980s, domestic and foreign scholars have done a great deal of research on it and are summarized as follows. 1 Definition Generally believed that fetal membranes rupture in the real prenatal, that is PROM. KUrhi et al [3] Then