【摘 要】
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BACKGROUND AND OBJECTIVEStudies have demonstrated that, when a patient presents with a periprosthetic joint infection (PJI) at a single site, there is a 15 % risk of PJI with prosthetic surgery at a s
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BACKGROUND AND OBJECTIVEStudies have demonstrated that, when a patient presents with a periprosthetic joint infection (PJI) at a single site, there is a 15 % risk of PJI with prosthetic surgery at a second site. This study was designed to determine whether there is a difference in the risk of PJI after a second total hip arthroplasty (THA) or total knee arthroplasty (TKA) among patients with previous PJI at other anatomical sites.
METHODSThis retrospective, matched, cohort study used databases of four academic institutions. The sample comprised 90 patients treated for PJI, subsequently undergoing a THA or TKA at another anatomical site. A control group comprised 90 patients who had had a prior THA or TKA procedure that was not complicated by PJI, who then underwent a second arthroplasty.
RESULTSTen of 90 patients in the sample had a second PJI, as compared with zero of 90 in the control group (P＝0.035). In patients with a prior history of PJI, a high frequency of second infection was noted in female patients and in patients whose initial infection was with staphylococcus species.
CONCLUSIONThis study of patients with a history of periprosthetic joint infection found that these individuals are at increased risk for infection with subsequent arthroplasties in other joints.
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