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目的了解昭平县1～6岁儿童乙肝疫苗免疫效果,为乙型肝炎的防控和乙肝疫苗接种提供科学理论依据。方法 2012年6月对昭平县150名儿童进行乙肝免疫效果调查,对所采集的血样采用美国雅培公司化学发光法定量检测HBsAg和HBsAb。结果共对150名儿童进行检测,HBsAg阳性率为0.67%(1/150),HBsAb阳性率为45.33%(68/150),性别之间HBsAb阳性率差异无统计学意义(P>0.05),各年龄组之间HBsAb阳性率差异有统计学意义(P<0.05)。结论昭平县1～6岁儿童HBsAg感染水平较低,HBsAb阳性率情况不容乐观,要加强乙肝防控知识的宣传,正确注射乙肝疫苗,加强抗体检测工作。
Objective To understand the immune effect of hepatitis B vaccine in children aged 1 ~ 6 years in Zhaoping County, and to provide a scientific basis for the prevention and control of hepatitis B and hepatitis B vaccination. Methods A total of 150 children in Zhaoping County were enrolled in this study. The collected blood samples were detected by Abbott chemiluminescence quantitative detection of HBsAg and HBsAb. Results A total of 150 children were tested. The positive rate of HBsAg was 0.67% (1/150) and the positive rate of HBsAb was 45.33% (68/150). There was no significant difference in the positive rate of HBsAb between the sexes (P> 0.05) The positive rates of HBsAb in all age groups were statistically significant (P <0.05). Conclusion The prevalence of HBsAg in children aged 1 ~ 6 years old in Zhaoping County is low, and the positive rate of HBsAb is not optimistic. It is necessary to strengthen the propaganda of hepatitis B prevention and control knowledge, inject hepatitis B vaccine correctly, and strengthen antibody testing.