论文部分内容阅读
在不少情况下,发现结核病的给药法可采用每周二次的冲击疗法,而无需每日服药。这种新的短程疗法,近来已经得到了局部承认。本文作者基于约1000个病例的试验,认为用异菸肼和利福平治疗九个月,可作为新病例所选择的治疗方案。这种疗法使结核菌阳性培养转阴较快,治疗失败和复发较旧疗法为少,毒性付作用发生率相似。其主要禁忌症是活动性肝炎。作者多采用异菸肼和乙胺丁醇,痰涂片阳性者加用链霉素。但当整个治疗周期不能同时联用二种杀菌药物时,治疗仍须延长至18~24个月。作者在治疗初期采用异菸肼300毫克/
In many cases, the method of administration of tuberculosis was found to use twice-weekly impact therapy instead of daily medication. This new short-range therapy has recently received partial recognition. Based on a trial of about 1,000 cases, the authors concluded that treatment with isoniazid and rifampicin for nine months can be the treatment of choice for new cases. This kind of therapy makes the positive culture of tubercle bacillus turn negative faster, the treatment failure and relapse are less than the old ones, and the incidence of toxic toxin effect is similar. Its main contraindication is active hepatitis. The authors used isoniazid and ethambutol, and sputum smear-positive patients were given streptomycin. However, when the entire treatment cycle cannot be combined with two kinds of bactericidal drugs at the same time, treatment must be extended to 18 to 24 months. The authors used isoniazid 300 mg at the beginning of treatment.