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目的探讨脐带血在新生儿ABO溶血病临床诊断中的价值。方法:选取我院2010年01月-2013年12月收治的疑似新生儿ABO溶血病患儿242例,随机分为对照组与观察组,每组121例,两组均行患儿红细胞直接抗人球蛋白、游离抗体、抗体释放三项试验,对照组于新生儿出生后检查确诊;观察组于新生儿出生前抽取脐带血检查确诊,观察两组新生儿ABO溶血病检出率。结果:检测结果显示,观察组抽取脐带血后的新生儿ABO溶血病阳性率可达98.35%;对照组新生儿出生后阳性率为66.12%,组间比较差异显著(P<0.05)。结论:新生儿ABO溶血病取脐带血行早期筛查与诊断,可达到早期发现与治疗目的,值得推广。
Objective To investigate the value of cord blood in the diagnosis of neonatal ABO hemolytic disease. Methods: A total of 242 children with suspected neonatal ABO hemolytic disease admitted to our hospital from January 2010 to December 2013 were randomly divided into control group and observation group, with 121 cases in each group. The two groups were given direct RBC resistance Human immunoglobulin, free antibody and antibody release were tested in the control group. The control group was diagnosed after birth, and the observation group was diagnosed by cord blood before the newborn was born. The detection rate of ABO hemolytic disease in the two groups was observed. Results: The results showed that the positive rate of neonatal ABO hemolytic disease in the observation group was 98.35% after the umbilical cord blood was drawn. The positive rate of neonatal birth was 66.12% in the control group with significant difference (P <0.05). Conclusion: Early screening and diagnosis of neonatal ABO hemolytic disease take umbilical cord blood can reach the purpose of early detection and treatment, which is worth promoting.