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本实验显示组胺H_2受体激动剂4-甲基组胺可促使更多的多能造血干细胞进入细胞周期,而组胺H_1受体激动剂2-甲基组胺则能拮抗4-甲基组胺的这一作用。4-甲基组胺与2-甲基组胺对造血干细胞周期状态的影响之间又呈现相互竞争现象。文中讨论了上述实验事实的理论意义。
This experiment shows that the histamine H 2 receptor agonist 4-methylhistamine can promote more pluripotent hematopoietic stem cells into the cell cycle, while the histamine H 1 receptor agonist 2-methylhistamine can antagonize 4-methyl Histamine this effect. 4-methylhistamine and 2-methylhistamine on the hematopoietic stem cell cycle status between the competition again showed the phenomenon. The paper discusses the theoretical significance of the above experimental facts.