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七十年代遗传工程学的发展给人们带来了研究肿瘤发病机理的有力工具。从病毒学家研究病毒与肿瘤关系开始至今才十多年,但已取得了超出人们预料的结果。癌基因的研究可能为人类最终认识癌变(包括病毒,化学和物理因素致癌)机制打下牢固基础。作者曾于去年对致癌基因研究现状做过综述,但近半年多来这方面研究突飞猛进的发展使得有必要再进行补充。一、细胞癌甚因(cellular oncogene)的活化癌基因(oncegene)是反转录病毒基因组中可造成动物细胞癌变的部分。由于已从人类膀胱、肺、结肠、胆囊、胰腺肿瘤以及横纹
The development of genetic engineering in the seventies has brought people a powerful tool for studying the pathogenesis of tumors. It has been more than ten years since virologists studied the relationship between viruses and tumors, but the results have exceeded the expectations. The study of oncogenes may lay a solid foundation for human beings to finally recognize the mechanism of carcinogenesis (including carcinogenesis of viruses, chemical and physical factors). The author reviewed the status of oncogene research last year, but the rapid development of research in this area over the past six months made it necessary to supplement it. First, cellular oncogene Activation Oncegene is part of the retroviral genome that can cause canceration of animal cells. As has been from the human bladder, lung, colon, gall bladder, pancreatic tumors and stripes