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我院1985年6月至1990年5月住院的新生儿黄疸患儿242例,其中21例经血清学确诊为ABO溶血病,占同期住院黄疸患儿的8.68%,现将21例病例分析如下。 临床资料 一、一般资料:男10例,女11例,均是足月顺产儿,体重2700~3800克,大多数患儿在3000克以上。第1胎20例,第2胎1例,该例有流产史3次。 二、临床表现:以黄疸出现快为临床特点,本组病例平均出现黄疸时间为27.4小时,其中1例生后2小时出现黄疸,生后24小时出现黄疸者7例,24~48小时11例,超过48小时3例,肝大肋下2cm者3例,肝功能均正常。 三、化验室检查:21例患儿母亲血型均为“O”型,患儿血型“A”型者8例,“B”型者13例,“B”型略多于“A”型。平均总胆红素为132μm-ol/L,最高1例为342μmol/L,且脐分泌物培养有金黄色葡萄球菌生长。21例中8例有轻度贫血,血红蛋
242 cases of neonatal jaundice were hospitalized in our hospital from June 1985 to May 1990, of which 21 cases were diagnosed as ABO hemolytic disease by serology, accounting for 8.68% of hospitalized jaundice in the same period. The analysis of 21 cases is as follows . Clinical data First, the general information: 10 males and 11 females, all full-term children, weighing 2700 ~ 3800 grams, most children in more than 3000 grams. The first child in 20 cases, the second child in 1 case, this case of abortion history 3 times. Second, the clinical manifestations: the clinical features of jaundice appear fast, the average incidence of jaundice in this group of patients was 27.4 hours, of which 1 case 2 hours after birth jaundice, 24 hours after birth jaundice in 7 cases, 24 to 48 hours in 11 cases , More than 48 hours in 3 cases, 3 cases of liver 2cm in the ribs, liver function were normal. Third, the laboratory tests: 21 cases of mothers blood type are “O” type, children with blood type “A” type in 8 cases, “B” type in 13 cases, “B” type slightly more than “A” type. The average total bilirubin 132μmol / L, the highest one case of 342μmol / L, and the growth of umbilical secretions Staphylococcus aureus. Eight of the 21 patients had mild anemia and hemoglobin