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分析血清葡萄糖(Glu)、乳酸(Lac)水平与动脉瘤破裂蛛网膜下腔出血患者预后的相关性.[方法]回顾性分析2015年2月至2018年1月安康市中心医院收治的71例动脉瘤性蛛网膜下腔出血患者的临床资料,根据患者预后情况分为预后不良组(n=27)和预后良好组(n=44).采用Logistic回归分析影响患者预后不良的独立影响因素,分析血清Lac、Glu及联合检测诊断动脉瘤性蛛网膜下腔出血患者预后不良的效能.[结果]预后不良组患者出血量、WBC、SCr、cTnI、Lac、Glu水平明显高于预后良好组患者,预后不良组患者Hunt-Hess分级及高血压比例高于预后良好组,差异有统计学意义(P<0.05).Logistic回归分析显示出血量、Lac、Glu、WBC、Hunt-Hess分级是患者预后不良的危险因素(P<0.05).血清Glu与mRS评分、出血量均呈正相关(r=0.678、0.734,均P<0.05);血清Lac与 mRS评分、出血量均呈正相关均呈正相关(r=0.681、0.705,均P<0.05).单独指标检测,血清Glu水平评估效能较高,其AUC高于血清Lac水平的AUC (Z=0.378,P=0.005),联合检测评估效能最高(ZGlu=2.061、ZLac=2.861,均P<0.05).[结论]血清Lac、Glu水平水平与动脉瘤性蛛网膜下腔出血患者预后不良相关,且血清Lac、Glu水平检测方便、快捷,对诊断具有一定的效能,而联合检测诊断患者预后不良的效能更高,对临床诊治有重要意义.“,”Toinvestigatecorrelationbetweenserum glucoseandlactatelevelsandprognosis inpatientswithaneurysmalsubarachnoidhemorrhage.[Methods]Theclinicaldataof71patientswithaneurys-malsubarachnoidhemorrhageadmittedtoourhospitalfrom February2015toJanuary2018 wereretrospec-tivelyanalyzed.Accordingtotheprognosisofpatientswithhemorrhagicsubarachnoidhemorrhage,patients wereclassifiedintothepoorprognosisgroup(n=27)andthegoodprognosisgroup(n=44).Serumglucose andbloodlactatelevelsweremeasuredinbothgroups.Logisticregressionwasusedtoanalyzetheindependent influencingfactorsofpatientswithpoorprognosis.Thereceiveroperatingcharacteristiccurve(ROC)wasused toanalyzetheefficacyofserumglucose(Glu),bloodlactate(Lac)andcombineddetectioninthediagnosisof poorprognosisinpatientswithaneurysmalsubarachnoidhemorrhage.[Results]Thelevelsofbleeding,WBC, SCr,cTnI,Lac,andGluinpatientswithpoorprognosisweresignificantlyhigherthanthoseinpatientswith goodprognosis.Theproportionof Hunt-Hessgradeandhypertensioninpatients withpoorprognosis was higherthanthatinpatientswithgoodprognosis.Thedifferencewasstatisticallysignificant(P<0.05).Lo-gisticregressionanalysisshowedthattheamountofbleeding,levelsofLac,Glu,and WBC,and Hunt-Hess gradingwereriskfactorsforpoorprognosis(P<0.05).Serum GlulevelwaspositivelycorrelatedwithmRS scoreandbloodloss(r=0.678,0.734,P<0.05).Serum LaclevelwasalsopositivelycorrelatedwithmRS score and blood loss ( r=0 .681 , 0 .705 , both P<0 .05 ) T he efficacy of seru m glucose diagnosis in patients withpoordiagnosisishigherthanthatofbloodlactate.Thecombineddetectionofserum glucoseandblood lactateismoreeffectivethansingleindicatorinpredictingprognosisofaneurysmalsubarachnoidhemorrhage.[Conclusion]Serumglucoseandbloodlactatelevelsarecloselyrelatedtopoorprognosisinpatientswithaneu-rysmalsubarachnoidhemorrhage,whichcanaccuratelyassesstheprognosisofpatients.Thedetectionofser-um LacandGlulevelsisconvenientandrapid,andhascertainefficacyfordiagnosis.Thecombineddetection anddiagnosisofpatientswithpoorprognosisismoreeffective,whichisofgreatsignificanceforclinicaldiag-nosisandtreatment.