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目的:研究干燥白花中华苦荬菜全草的化学成分。方法:采用硅胶柱色谱、HPLC、重结晶等方法进行分离纯化,依据理化性质和波谱数据鉴定结构。结果:从白花中华苦荬菜全草中分离得到15个化合物,分别鉴定为:对羟基苯乙酸甲酯(1)、β-谷甾醇葡萄糖苷(2)、β-谷甾醇(3)、木樨草素-7-O-β-D-葡萄糖苷(4)、15-羟基-1(10),3,11(13)-愈创木三烯-12,6-内酯-2-酮(5)、Chinensiolide B(6)、Chinensiolide E(7)、Ixerochinoside(8)、Chinensiolide C(9)、10α-羟基-4(15)-愈创木烯-12,6-内酯(10)、10α-羟基-4(15),11(13)-愈创木二烯-12,6-内酯-3β-O-β-D-(6’-对羟基苯乙酰氧基)葡萄糖苷(11)、黑麦草素(12)、芹菜素-7-O-β-D-葡萄糖苷(13)、木樨草素(14)、叶黄素(15)。结论:其中,化合物1、10、11、12、15为首次从该植物中分离得到。
Objective: To study the chemical constituents of the whole plant of Chinese white bitter Chinese cabbage. Methods: The compounds were separated and purified by silica gel column chromatography, HPLC and recrystallization. The structure was identified by physicochemical properties and spectral data. Results: Fifteen compounds were isolated from the whole plant of Acacia crassiculla, identified as p-hydroxybenzene acetic acid methyl ester (1), β-sitosterol glucoside (2), β-sitosterol 7-O-β-D-glucoside (4), 15-hydroxy-1 (10), Chinensiolide B (6), Chinensiolide E (7), Ixerochinoside (8), Chinensiolide C (13) -guaioga-12,6-lactone-3β-O-β-D- (6’-p-hydroxyphenylacetoxy) glucoside (11 ), Ryegrass (12), apigenin-7-O-β-D-glucoside (13), clodonin (14) and lutein (15). Conclusion: Among them, compounds 1,10,11,12,15 were isolated from this plant for the first time.