,Comparison of high-sensitivity C-reactive protein level between systemic and coronary circulation i

• 作 者: Haoyu Meng Min Zhang Pengsheng Chen Ze-Mu Wang Bo Chen Zhijian Yang
• 机 构: Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 21002
• 出 处: 生物化学与生物物理学报（英文版）
• 发表日期: 2014年2期

Inflammation plays an important role not only in the initiation and progression of atherosclerosis but also in plaque rupture of coronary artery disease (CAD) [1-3],which leads to acute coronary syndrome (ACS) or even acute myocardial infarction (AMI).It is well known that C-reactive protein (CRP) is one of the most important inflammation markers and has been proved to be an independent risk factor for CAD [4-7].High level of CRP predicts poor clinical outcomes in patients with both stable CAD and ACS [6-9].Compared with CRP,high-sensitivity CRP (hs-CRP) is more sensitive that can be examined in serum.However,the source of CRP or hs-CRP in CAD or ACS has not been definitively explored.