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为了探讨颈动脉粥样硬化程度、性质特点和脑卒中的关系,对14例脑卒中病例(脑出血7例,脑梗塞7例)的颈动脉进行了病理观察及形态定量分析。结果显示:脑出血病灶侧颈动脉存在明显粥样硬化性狭窄,P<0.05,脑梗塞患者的颈动脉粥样硬化程度重于脑出血,尤以颈内动脉表现为著,P<0.05,脑梗塞患者的颈动脉粥样硬化斑块具备不稳定的组织学特性,为夹层动脉瘤,动脉内膜溃疡,附壁血栓或质地松散,密度不均易脱落的斑块。该研究提示:颈动脉狭窄的程度与脑出血或脑梗塞均相关,若粥样硬化斑块为不稳定状态,则是脑梗塞发病的重要病因。
In order to explore the relationship between carotid atherosclerosis, nature and stroke, the pathology and morphometric analysis of 14 carotid arteries in stroke patients (7 with cerebral hemorrhage and 7 with cerebral infarction) were performed. The results showed that there was obvious atherosclerotic stenosis in the side carotid artery of cerebral hemorrhage, P <0.05. The degree of carotid atherosclerosis in patients with cerebral infarction was more severe than that in intracerebral hemorrhage, especially in the internal carotid artery, P <0 .05, Carotid atherosclerotic plaques in patients with cerebral infarction with unstable histological features, dissection aneurysms, arterial intimal ulcers, mural thrombus or loose texture, easy to fall off the density of plaques. The study suggests that: the degree of carotid stenosis and cerebral hemorrhage or cerebral infarction are related, if the atherosclerotic plaque is unstable, is an important cause of cerebral infarction.