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本文研究了重症慢性活动性肝炎(慢活肝)经皮质类固醇治疗,使肝脏形态学改善为慢性迁延性肝炎(慢迁肝)而停药后的预后。对临床、生化和免疫学等可能预示后来发生变化的检查结果也进行了估价。方法:52例重症慢活肝成人患者经强的松治疗18±2个月后,组织学检查显示慢迁肝。37例为妇女,其中32例在治疗前6个月具有各种症状。入院时平均年龄为36±2岁,平均发病时间为11±3个月。治疗前,组织学变化有中度至重度汇管区周围肝炎者24例,带
This article studies the prognosis of patients with severe chronic active hepatitis (slow-living liver) treated with corticosteroids, which improved the morphology of the liver to chronic persistent hepatitis (slow-moving liver). The clinical, biochemical and immunological tests, which may indicate later changes, are also valued. Methods: Fifty-two patients with severe chronic active liver disease were treated with prednisone for 18 ± 2 months. Histological examination showed that the liver was slowly migrated. Thirty-seven women were women, 32 of whom had various symptoms six months prior to treatment. The average age at admission was 36 ± 2 years, with an average onset time of 11 ± 3 months. Before treatment, histological changes in moderate to severe portal area around the hepatitis 24 cases, with