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骨钙素来源于骨组织,是一种维生素K依赖性蛋白质;在维持体内钙磷代谢平衡方面起着重要作用。它增加成骨细胞的反应性,因此,也可作为前列腺癌骨转移的标记物。作者测定52例晚期前列腺癌病人的血清骨钙素,并随访观察病人接受内分泌治疗后骨钙素的变化。旨在获得对前列腺癌骨转移的早期诊断及治疗期间对骨转移灶监测的价值。同时,就其敏感性和特异性与PSA和PAP作了比较研究。前列腺癌52例;年龄:65～79岁。其中C期25
Osteocalcin is derived from bone tissue and is a vitamin K-dependent protein; it plays an important role in maintaining calcium and phosphorus metabolism in the body. It increases the reactivity of osteoblasts and therefore can also serve as a marker for prostate cancer bone metastases. The authors measured serum osteocalcin in 52 patients with advanced prostate cancer and followed up for changes in osteocalcin after endocrine therapy. The aim is to obtain the value of bone metastases monitoring in the early diagnosis of prostate cancer bone metastases and during treatment. At the same time, a comparative study of PSA and PAP was made on its sensitivity and specificity. 52 cases of prostate cancer; age: 65 to 79 years old. Of which C period 25