Effects of minocycline on learning and memory of mice following ischemic-hypoxic cerebral injuries

• 作 者: Hongling Fan Yuanyin Zheng Lij
• 机 构: DepartmentofPhysiology
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2012年2期
• 关键词: 缺氧性 脑损伤 小鼠 缺血 记忆 学习 生理盐水 形态学变化 minocycline ischemic-hypoxic cerebral injury le
• 基金项目: Fan HL, Zheng YY, Xu L J, Zhong ZC, Cai SN, Zhang SL, Chang QZ. Effects of minocycline on learning and memory of mice following ischemic-hypoxic cerebral injuries. Neural Regen Res. 2012,7（2）：114-118.

An ischemic-hypoxic animal model was established using right common carotid artery occlusions and inhalation of low concentrations of oxygen in mice. At 10 days after the ischemic-hypoxic injuries, saline-treated mice exhibited significantly prolonged esc