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将64例患者根据静脉血浆葡萄糖值分糖尿病组36例、糖尿病前期组28例,观察两组的血糖水平,并测定两组血清CRP、糖脂代谢指标和胰岛功能,将CRP与糖脂代谢指标、胰岛功能作相关性分析。结果:CRP在糖尿病组和糖尿病前期组有显著差异(P<0.05),CRP水平与血糖、HbAlc、BMI、TC、TG、LDL-C呈正相关(P<0.01),与胰岛功能指数成负相关(P<0.01)。结论:提示CRP与2型糖尿病患者胰岛功能减退的发生、发展有一定相关性。
Sixty-four patients were divided into three groups according to the value of venous plasma glucose: 36 cases of diabetes mellitus and 28 cases of pre-diabetic group. The levels of blood glucose, glucose and lipid metabolism and islet function were measured in both groups. CRP and glucose and lipid metabolism , Islet function for correlation analysis. Results: CRP was significantly different between diabetic group and pre-diabetic group (P <0.05). CRP level was positively correlated with blood glucose, HbAlc, BMI, TC, TG and LDL-C (P <0.01). Conclusion: It is suggested that there is a certain correlation between CRP and the occurrence and development of islet hypofunction in type 2 diabetic patients.