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人体具有对自身组织产生抗体或致敏淋巴细胞并发生免疫反应的能力,其生理意义在于协助清除衰老或损伤的细胞。当此反应超过一定限度则可造成对自身组织的损伤,在此情况下能导致自身免疫病的发生。目前已认识到不少疾病的发病机理与自身免疫反应有关;许多自身免疫病常可侵犯多个组织、器官。眼部的结膜、角膜、巩膜、葡萄膜、视网膜、肌肉、神经、血管等均可成为自身免疫反应的“靶”器官。充分认识自身免疫病的眼部表现在临床上有一定意义。现收集有关资料作一综述。本文不包括局限于眼部的一些自身免疫病,如外伤后交感性眼炎,手术后眼炎等;也不包括文献中已有较多介绍的一些自身免疫病,如Behcet病、甲亢、Sj(?)gren综合征等。一、巨细胞动脉炎和风湿性多发性肌痛症巨细胞动脉炎为全身中一大口径动脉的炎症
The human body has the ability to produce antibodies or sensitized lymphocytes to its own tissues and develop an immune response whose physiological significance is to assist in the removal of aged or damaged cells. When the reaction exceeds a certain limit can cause damage to their own tissues, in this case can lead to the occurrence of autoimmune diseases. It has been recognized that the pathogenesis of many diseases and autoimmune reactions; many autoimmune diseases often can invade multiple tissues and organs. Ocular conjunctiva, cornea, sclera, uvea, retina, muscle, nerve, blood vessels, etc. can become the “target” of the immune response. Full understanding of the autoimmune diseases of the eye has clinical significance. We are collecting relevant information for a review. This article does not include some of the autoimmune diseases that are confined to the eye, such as post-traumatic sympathetic ophthalmia, postoperative ophthalmia and so on; nor does it include some autoimmune diseases that have been described in more detail in the literature, such as Behcet’s disease, hyperthyroidism, Sj (?) gren syndrome and so on. First, giant cell arteritis and rheumatic polymyositis giant cell arteritis is the body of a large diameter artery inflammation