论文部分内容阅读
Wegener肉芽肿病为一少见疾病。鉴于本病临床、病理变化多端,与许多疾病有相似之处,常导致误诊,在文献上亦常以多种名称出现,比较混乱。因此,将所见有关文献作一复习。一、命名及分类 Klinger于1931年首次记述2例毁损性副鼻窦炎、肾炎及尿毒症,尸检发现脾脏肉芽肿,动脉炎及肾小球损害,称“结节性动脉周围炎的边缘病例”。至1939年,Wegener先后报道3例残毁性肉芽肿性鼻炎,伴有明显的肺部征候、肾小球肾炎及泛发性脉管炎,认为是结节性多动脉炎的变种,将其命名为“鼻源性肉芽肿(Rhinogenic granuloma)”。后
Wegener’s granulomatosis is a rare condition. In view of the clinical and pathological changes of the disease, it has many similarities with many diseases and often leads to misdiagnosis. It is often confused with various names in the literature. Therefore, I will review the relevant literature for a review. First, the name and classification Klinger first described in 1931 2 cases of devastating sinusitis, nephritis and uremia, autopsy found granuloma of the spleen, arteritis and glomerular damage, called “the edge of nodular periarteritis cases” . To 1939, Wegener has reported 3 cases of ruptured granulomatous rhinitis, with obvious signs of the lungs, glomerulonephritis and generalized vasculitis, that is a variant of polyarteritis nodosa, its Named “Rhinogenic granuloma.” Rear