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用尾静脉汪射金黄色葡萄球菌L型(2.0×107个/0.2ml/次/只)反复感染昆明种小民为L型组.注射原菌(金葡菌)和生理盐水的小民分别作为对照组。试验结果证实,L型组有7的发生肿瘤,发瘤率为11.7%,其中恶性肿瘤5例,良性肿瘤2例。恶性肿瘤中3例为癌.2例为淋巴瘤;而原菌组和生理盐水组均未见肿瘤。L型组有58.3%的鼠发生癌前病变,明显高于原菌组(1.3%).P<0.05.生理盐水组未见癌前病变。小民恶性肿瘤和癌前病变的发生率随实验天数的延长和感染次数的增加有逐渐升高的趋势。结果提示,L型能诱发小鼠肿瘤并使癌前病变的发生率明显增加。本文并对L型诱发小民肿瘤的可能因素进行了讨论。
The tail vein vein staphylococcus aureus L-type (2.0 × 107 /0.2ml / times / only) repeatedly infected Kunming Kominka L-shaped group. Injecting the original bacteria (Staphylococcus aureus) and saline small people as a control group. The test results confirmed that L-type group of 7 tumors occurred, the incidence of tumor was 11.7%, of which 5 cases of malignant tumors, benign tumors in 2 cases. 3 cases of cancer in cancer. 2 cases of lymphoma; while the original bacteria group and saline group were no tumor. 58.3% rats in L group had premalignant lesion, which was significantly higher than that of the original group (1.3%). P <0.05. Saline group no precancerous lesions. The incidence of small malignant tumors and precancerous lesions with the experimental days and the number of infections increased gradually increased trend. The results suggest that L-type mice can induce tumor and the incidence of precancerous lesions increased significantly. This article also discussed the possible causes of L-type small tumors induced.