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检测３０例乙型肝炎后肝硬化失代偿期的病人红细胞超氧化物歧化酶（ＳＯＤ），谷胱甘肽过氧化物酶（ＧＳＨＰｘ）活力，丙二醛（ＭＤＡ）含量，红细胞Ｃ３ｂ受体及免疫复合物（ＩＣ）受体花环率。结果表明，肝硬化组红细胞ＳＯＤ、ＧＳＨＰｘ活力明显降低（Ｐ＜００１），ＭＤＡ含量明显升高（Ｐ＜００１），红细胞Ｃ３ｂ受体花环率明显降低（Ｐ＜００１），ＩＣ受体花环率明显升高（Ｐ＜００１）；肝硬化病人红细胞ＳＯＤ、ＧＳＨＰｘ活力与ＩＣ受体花环率呈负相关（ｒ１＝－０．６４，Ｐ＜０．０１；ｒ２＝－０．８７，Ｐ２＜０．０１），红细胞ＭＤＡ含量与ＩＣ受体花环率呈正相关（ｒ＝０．６４，Ｐ＜０．０１）。本结果提示，肝硬化病人红细胞抗氧化能力及免疫功能的降低对肝硬化的发展有重要影响
To detect the activity of erythrocyte superoxide dismutase (SOD), glutathione peroxidase (GSH-PX), malondialdehyde (MDA), erythrocyte C3b in 30 patients with decompensated cirrhosis after hepatitis B Receptor and immune complex (IC) receptor rosette rate. The results showed that the activities of SOD and GSH-Px in erythrocyte of liver cirrhosis group were significantly decreased (P <001), MDA content was significantly increased (P0.01), the rosette rate of erythrocyte C3b receptor was significantly decreased (P0.01 ), The rosette rate of IC receptor was significantly increased (P <001). The activity of SOD and GSH-Px of erythrocytes in cirrhotic patients was negatively correlated with the rate of IC rosette (r1 = -0.64, P <0.01) ; R2 = -0.87, P2 <0.01). The content of MDA in erythrocytes was positively correlated with the rate of ICR (r = 0.64, P <0.01). The results suggest that the reduction of erythrocyte antioxidant capacity and immune function in patients with cirrhosis has a significant impact on the development of cirrhosis