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目的:探讨中医分型论治结合西医常规治疗方法在治疗小儿紫癜性肾炎中的疗效。方法:采用随机对照的方法,对照组常规应用肾上腺皮质激素、维生素C、潘生丁等治疗,实验组在对照组用药的基础上辨证分型论治。治疗4周后观察前后24h尿蛋白定量、尿红细胞计数和肾功能变化。结果:实验组总有效率明显优于对照组(Z=-3.013、P=0.003)。实验组在减少尿蛋白量及红细胞计数和疗效方面均优于西医组,差异有统计学意义(P<0.01,P<0.05)。结论:中医分型论治结合西医常规治疗是一种起效快、控制症状全面的治疗手段,值得临床医生借鉴。
Objective: To investigate the curative effect of traditional Chinese medicine (TCM) on the treatment of purpura nephritis in children with the combination of traditional Chinese medicine and western medicine. Methods: The control group was treated with adrenal cortical hormone, vitamin C and dipyridamole by randomized and controlled methods. The experimental group was treated by the control group with syndrome differentiation. After 4 weeks of treatment, urinary protein excretion, urine red blood cell count and renal function were observed before and after treatment. Results: The total effective rate of the experimental group was significantly better than that of the control group (Z = -3.013, P = 0.003). The experimental group was superior to western medicine group in reducing urinary protein, erythrocyte count and therapeutic effect (P <0.01, P <0.05). Conclusion: The combination of traditional Chinese medicine and traditional Chinese medicine treatment is a rapid onset of treatment of symptoms and signs of comprehensive treatment, it is worth learning from clinicians.