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目的探讨中西医结合治疗小儿难治性癫痫的临床效果。方法 60例难治性癫痫患儿,随机分为实验组和对照组,每组30例。对照组接受常规西医治疗,实验组接受中西医结合治疗,对两组患儿的临床治疗效果进行比较,并检测血浆丙二醛水平和总抗氧化能力水平。结果经治疗后,实验组患儿总有效率为90.0%(27/30),对照组为73.3%(22/30),比较差异有统计学意义(P<0.05);两组患儿治疗后血浆丙二醛水平和总抗氧化能力水平和治疗前比较显著改善,实验组患儿改善更加明显,差异有统计学意义(P<0.05)。结论小儿难治性癫痫运用中西医结合的治疗方法能够产生显著效果,保证患儿体内自由基水平得到改善,进一步阻止神经元放电,对其脑组织进行保护,缓解其癫痫症状,值得在临床治疗中进行使用和推广。
Objective To explore the clinical effect of integrated traditional Chinese and western medicine in the treatment of refractory epilepsy in children. Methods Sixty children with refractory epilepsy were randomly divided into experimental group and control group, 30 cases in each group. The control group received routine western medicine treatment. The experimental group received Integrative Chinese and Western medicine treatment. The clinical effects of the two groups were compared. The level of plasma MDA and total antioxidant capacity were also measured. Results After treatment, the total effective rate was 90.0% (27/30) in the experimental group and 73.3% (22/30) in the control group, the difference was statistically significant (P <0.05). After treatment, Plasma MDA levels and total antioxidant capacity were significantly improved compared with those before treatment. The improvement in the experimental group was more obvious with significant difference (P <0.05). Conclusion Treatment of pediatric intractable epilepsy with combination of TCM and WM can produce significant effect to ensure that the level of free radicals in children is improved, further prevent the neurons from discharging, protect their brain tissue and relieve the symptoms of epilepsy, which is worthy of clinical treatment In the use and promotion.