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129例肾移值患者,术后真菌感染率为17.1％,死亡率为18.1％。感染率随年龄增长而增高,女性略高于男性(P<0.10),尿路感染占首位(35.1％)。真菌感染绝大多数(86.4％)发生在术后2个月以内,故认为此期为肾移植术后真菌感染危险期。肾移植术后易引起真菌感染的危险因素包括:①长期大量应用广谱抗生素;②排异反应和免疫抑制剂的治疗;③术后保留导尿管和支架管;④尿漏及伤口出血等外科并发症;⑤末梢白细胞减少;⑥糖尿病包括并发类固醇性糖尿病;⑦蛋白质营养不良等。
129 cases of renal transplant patients, postoperative fungal infection rate was 17.1%, the mortality rate was 18.1%. Infection rate increased with age, women were slightly higher than men (P <0.10), urinary tract infection accounted for the first (35.1%). The vast majority of fungal infections (86.4%) occurred within 2 months after operation, so this period is the risk of fungal infection after renal transplantation. The risk factors of fungal infections after renal transplantation include: ① long-term large-scale use of broad-spectrum antibiotics; ② rejection and immunosuppressive therapy; ③ postoperative catheter and stent retention; urinary leakage and wound bleeding Surgical complications; ⑤ peripheral leukopenia; ⑥ diabetes, including concurrent steroid-induced diabetes; ⑦ protein malnutrition and so on.