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目的:探讨阿奇霉素联合激素治疗难治性支原体肺炎(RMP)的临床效果。方法:选取在我院治疗的RMP患儿100例为研究对象,按入院顺序分为对照组和研究组各50例。对照组给予阿奇霉素静脉滴注治疗,研究组在阿奇霉素常规治疗的基础上给予静脉滴注甲泼尼龙琥珀酸钠,观察两组患儿的临床症状和体征消失时间、临床疗效及不良反应。结果:研究组患儿症状消失时间、住院时间以及不良反应发生率明显低于对照组(P<0.05)。研究组患儿治疗的总有效率为98.0%,明显高于对照组的44.0%(P<0.05)。结论:阿奇霉素联合激素有助于改善RMP患儿的临床症状和体征,提高疗效,降低不良反应的发生率。
Objective: To investigate the clinical effect of azithromycin combined with hormone therapy in the treatment of refractory mycoplasma pneumonia (RMP). Methods: 100 cases of RMP children who were treated in our hospital were selected as the research object, divided into control group and study group according to admission sequence, 50 cases each. The control group was treated with intravenous infusion of azithromycin. The study group was given intravenous methylprednisolone sodium succinate on the basis of routine treatment of azithromycin. The clinical symptoms and signs disappeared, clinical efficacy and adverse reactions were observed in both groups. Results: The symptom disappearance time, hospital stay and incidence of adverse reactions in study group were significantly lower than those in control group (P <0.05). The total effective rate of the treatment group was 98.0% in the study group, which was significantly higher than that in the control group (44.0%, P <0.05). Conclusion: Azithromycin combined with hormones can help to improve the clinical symptoms and signs of children with RMP, improve the curative effect and reduce the incidence of adverse reactions.