【摘 要】
：
人微生物菌群是指由寄生在人皮肤及黏膜等部位的细菌、病毒、真菌和原生动物组成的微生物群。通常情况下，微生物菌群同宿主之间保持稳态，共同参与人的生命活动，而当致病菌或机会
【机 构】
：
上海交通大学医学院附属新华医院普通外科 200092;上海交通大学医学院附属仁济医院胆胰外科 200127
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人微生物菌群是指由寄生在人皮肤及黏膜等部位的细菌、病毒、真菌和原生动物组成的微生物群。通常情况下，微生物菌群同宿主之间保持稳态，共同参与人的生命活动，而当致病菌或机会致病菌异常侵入或富集时可引起菌群失调，从而引起疾病。近些年来，微生物菌群失调与疾病特别是恶性肿瘤的关系成为临床研究的热点。笔者根据国内外研究进展，就肝胆肿瘤与微生物菌群失调关系的研究进展进行综述。“,”Human microbial microbiota refer to bacteria, viruses, fungi and protozoa which colonized on human skin and mucous membrane. Under normal circumstances, the microbial microbiota maintain local homeostasis with the host and participate in human life activities. However, when the pathogenic bacteria or opportunistic pathogens abnormally accumulate, the balance of microbial microbiota and host will be destroyed, and thus cause the emergence of diseases. Currently, the relationship between dysbacteriosis and diseases, especially malignant tumors, has become a hotspot in clinical research. The authors review the research advance in the relationship between hepatobiliary tumors and the disorder of microflora based on the research progress at home and abroad.
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