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本研究在发现甘氨酸具有拮抗内毒素作用的基础上,进一步观察了甘氨酸对内毒素与单核细胞结合率的影响及甘氨酸改变内毒素的超微结构。运用流式细胞仪检测表明,正常情况下,异硫氰酸盐标记的内毒素与单核细胞结合的百分比为85.2%±1.6%,单核细胞表面萤光强度值为3.03±0.19;在加入甘氨酸后,内毒素与单核细胞结合的百分
In this study, glycine was found to antagonize endotoxin on the basis of further observation of glycine on the binding rate of endotoxin and monocytes and glycine to change the endotoxin ultrastructure. The results of flow cytometry showed that under normal conditions, the percentage of isothiocyanate-labeled endotoxin binding to monocytes was 85.2% ± 1.6% and the fluorescence intensity of mononuclear cells was 3.03 ± 0.19. After adding Glycine, the percentage of endotoxin binding to monocytes