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本实验采用原子吸收分光光度法对12名健康志愿者的血药浓度进行了测定,并分别用交叉实验设计的方法比较了葡萄糖酸锌片剂,胶囊剂与其原料粉的相对生物利用度,结果:两种制剂的相对生物利用度分别为75.56%和91.38%。
In this study, plasma concentrations of 12 healthy volunteers were determined by atomic absorption spectrophotometry. The relative bioavailability of zinc gluconate tablets, capsules and their raw powders were compared by cross-experimental design. Results The relative bioavailability of the two formulations was 75.56% and 91.38%, respectively.