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肾性尿崩症(NDI)是一种较少见的疾病。患病时肾脏对抗利尿激素无反应。在2～3岁左右能主动饮水前,主要临床特征是脱水,以后表现为多尿、烦渴。有些病人智力发育延迟,多认为是早年长期高渗脱水所致。早期诊治可防止发育异常。治疗主要是供水、低溶质饮食和利尿剂,使NDI患者降低尿量达20～55％。但尿量仍过大,故需经口摄入更多液体。婴幼儿常需静脉或胃管给水。大量摄水可致遗尿、呕吐、食欲不佳和生长障碍。本文报告用前列腺素合成酶抑制剂治疗两例NDI
Renal diabetes insipidus (NDI) is a less common disease. When the disease kidney anti-diuretic hormone no response. Before the age of 2 to 3 years can take the initiative to drink water, the main clinical features of dehydration, after the performance of polyuria, polydipsia. Delayed mental development in some patients, more thought to be caused by long-term hypertonic dehydration. Early diagnosis and treatment to prevent dysplasia. Treatment is mainly water, low solute diet and diuretics, NDI patients to reduce the amount of urine up to 20 to 55%. However, the urine output is still too large, so oral intake of more liquid. Infants and young children often need intravenous or tube water. Large amount of water can cause enuresis, vomiting, poor appetite and growth disorders. This article reports the treatment of two NDIs with prostaglandin synthase inhibitors