Effects of Chinese herb compound 962 on dementia- like rat models

• 作 者: 李林 李斌 刘汇波 安文林 叶翠飞 张丽 何士大
• 机 构: Department of Pharmacology, Xuan-Wu Hospital of Capital University of Medical Sciences, Beijing Geri
• 出 处: Acta Pharmacologica Sinica
• 发表日期: 1999年07期
• 关键词: ligation bilateral carotid permanent rodent indicators acetylcholine basal estro

AIM: To investigate whether Chinese herb compound 962 couldimprove the learning--memory ability and related indicators indemntia-like rodent models. MEHTODS:962 powder wasextracted from 6 kinds of Chinese medical herbs and fed to theanimals through syringe for 1-2 months. The animal modelsincluded: (1) injection of ibotenic acid into basal forebrain of rats(IBO-model); (2) rats at the age of 20-24 months (agedmodel) and (3) permanent ligation of bilateral common carotid

AIM: To investigate whether Chinese herb compound 962 could immit the learning--memory ability and related indicators indemntia-like rodent models. MEHTODS:962 powder was extracted from 6 kinds of Chinese medical herbs and fed to the animals through syringe for 1-2 months. Animal modelsincluded: (1) injection of ibotenic acid into basal forebrain of rats (IBO-model); (2) rats at the age of 20-24 months (agedmodel) and (3) permanent ligation of bilateral common carotid