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恶性黑素瘤可常规地根据病史、临床表现及病理组织学检查加以诊断,但有不少病例诊断较困难。近年来,已采用单克隆抗体(McAb)对本病进行研究,并开始应用于诊断与治疗。本文作者报道用~(111)In标记抗人黑素瘤鼠型McAb(ZME-108)诊断1例无黑色素性黑素瘤。患者23岁,男性,自1987年6月中旬,发现右后颈部有一拇指头大小的皮下肿物。同年7月6日行手术切除。术后不久肿瘤复发,并迅速增大。查体,右后颈部手术瘢痕下有一
Malignant melanoma can be routinely diagnosed based on medical history, clinical manifestations, and histopathological examinations, but many cases are difficult to diagnose. In recent years, monoclonal antibodies (McAbs) have been used to study the disease and have begun to be used for diagnosis and treatment. The authors report the diagnosis of one case of amelanotic melanoma using a (111) In labeled anti-human melanoma murine McAb (ZME-108). The patient was 23 years old and male. From mid-June 1987, a subcutaneous tumor of the size of the thumb head was found in the right posterior neck. On July 6 of the same year, surgical resection was performed. The tumor recurred shortly after the operation and rapidly increased. Physical examination, a scar under the right back neck surgery