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问:贵刊1989年第8卷第1期35页一文中,曾多次提到阿斯匹林与Reye氏综合征的关系,请问什么是Reye氏综合征? 答:Reye是人名,通常译作“雷耶”。氏等于1963年首先描述了小儿突然发生急性神经精神症状、发热、低血糖、肝功能异常等临床表现,病理检查有脑水肿和肝肾等脏器变性。当时,由于医疗水平所限,患儿均在入院后二天内死亡。根据近10年来医学文献的报道,本综合征的病因虽不明确,但认为可能与病毒有关。流行病学的凋查显示,在患雷耶氏综合征之前,有60～70％的患儿曾患流感,20～30％曾患水痘,5～10％曾患胃肠炎。在水痘或胃肠炎之后继发此综合征的患儿,平均
Q: In your article, Volume 8, Number 1, 1989, No. 35, 1989, you have repeatedly mentioned the relationship between aspirin and Reye’s syndrome. What is Reye’s syndrome? Reye. ’S equivalent to 1963 first described the sudden onset of acute neuropsychiatric symptoms in children, fever, hypoglycemia, liver dysfunction and other clinical manifestations of brain edema and liver and other organ degeneration. At that time, children were both killed within two days after admission due to medical limitations. According to medical reports in the past 10 years, although the etiology of this syndrome is not clear, but may be related to the virus. Epidemiological investigations show that 60-70% of children have had flu before suffering from Reye’s syndrome, 20-30% have chickenpox, and 5-10% have had gastroenteritis. Children with this syndrome secondary to chickenpox or gastroenteritis are on average