Hepatitis C virus-specific cytotoxic T cell response restoration after treatment-induced hepatitis C

• 作 者: Juan-RamónLarrubia EliaMo
• 机 构: EduardoSanz-de-Villalobos,DepartmentofMedicineandMedicalSpecialties,DepartmentofBiologyofSystems
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2015年12期
• 关键词: HEPATITIS C VIRUS CHRONIC HEPATITIS HEPATITIS C vi Hepatitis C virus Chronic hep
• 基金项目: Supported by“Instituto de Salud Carlos III”,Spain and“European Regional Development Fund,a way of making Europe”,E.U.(PI12/00130)； Moreno-Cubero E was funded by a research award from“Asociación d

Hepatitis C virus(HCV)-specific cytotoxic T cell(CTL) response plays a major role in viral control during spontaneous infection resolution. These cells develop an exhausted and pro-apoptotic status during chronic onset, being unable to get rid of HCV. The