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肿瘤的导向治疗是近20年内发展起来的肿瘤治疗手段。早在1903年Ehrlich就提出用“魔弹”治疗肿瘤的构想。直至80年代,随着抗体技术的进步,尤其是单克隆技术的出现,肿瘤的导向治疗才从设想成为现实,即利用抗肿瘤抗体对肿瘤抗原的特异性识别,携带细胞毒物质特异性杀伤肿瘤,故有人称之为“生物导弹”。肝癌的导向研究在肿瘤的导向研究中占有相当重要的地位,肝癌是导向研究较早进入临床的观察对象,1980年Order首先用~(131)Ⅰ标记抗体对肝癌进行导
Tumor-directed therapy is a method of tumor treatment developed in the last 20 years. As early as 1903, Ehrlich proposed the concept of using the “magic bullet” to treat tumors. Until the 1980s, with the advancement of antibody technology, especially the emergence of monoclonal technology, the cancer-targeted therapy became a reality from the point of view, that is, the use of anti-tumor antibodies to specifically recognize tumor antigens and carry cytotoxic substances to specifically kill tumors. Some people call it “biological missile.” The research of liver cancer orientation plays an important role in tumor-oriented research. Liver cancer is an early target of clinical research. In 1980, Order first used ~(131)I-labeled antibodies to induce liver cancer.