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本文应用原位杂交组化方法研究了降钙素基因相关肽（CGRP）的。α－和β－两种亚型的mRNA及编码P物质（SP）的前原速激肽AmRNA（PPTAmRNA大鼠三叉神经节神经元中的表达状况。结果发现：大约有35．7％，22．3％和17．5％的三叉神经节神经元分别有α－CGRP，β－CGRP和PPTA－mRNTA表达。中、小型神经元含有上述三种肽的mRNAs，而大神经元则主要表达。α－CGRPmRNA，从而提示它们在感觉信息的传递过程中可能起着不同的作用。相邻切片法研究的结果发现：这三种肽的mRNAs可共同表达于一些中、小神经元中，提示SP和CGRP在功能上的密切关系。
In this study, CGRP was studied by in situ hybridization. The mRNAs of α- and β-subtypes and the pre-proTK AmRNA encoding substance P (SPTA) (the expression status in the trigeminal ganglion neurons of the PPTAmRNA rat were found to be approximately 35.7%, 22. 3% and 17.5% of the trigeminal ganglion neurons expressed α-CGRP, β-CGRP and PPTA-mRNTA, respectively.Middle and small neurons contained mRNAs of the above three peptides, while the major neurons expressed mainly α -CGRPmRNA, suggesting that they may play a different role in the process of sensory information transmission.As a result of the adjacent slicing method, the mRNAs of these three peptides can be co-expressed in small and medium neurons, suggesting that SP and CGRP is closely related in function.