Signals of painful diabetic neuropathy (PDN) are believed to originate in the peripheral nervous system.But its peripheral mechanism ofhyperalgesia has rema
For optimal function, alternative pre-mRNA splicing is an exquisite mechanism to expand Cav1.2 channel electrophysiological and pharmacological properties b
In many neurons, a numbcr of receptors coupled to the Gq/11 family of G proteins modulate "M-type" (KCNQ, Kv7) K+ channels and voltage-gated Ca2+ channels (